https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48700 Wed 29 Mar 2023 11:35:00 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35094 Thu 20 Jun 2019 15:56:20 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12950 1) between patient cohorts receiving specialised care for different lengths of time. Results: Improved mean height z-score (−0.880 v −0.047) and weight centile (28.3% v 48.1%) for the 10–15 year age group in 1997, who had received continuous lifetime care within the clinic, compared with the same age group in 1993, for whom continuous medical care started at an older age. There was no corresponding improvement in FEV₁, as an indicator of lung function, in this group (81.6% predicted v 89.5% predicted). Conclusions: This study suggests that lifetime continuous care within a specialised CF centre is associated with improved growth but not improved lung function.]]> Sat 24 Mar 2018 08:18:29 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:21233 P < 5 × 10⁻⁸) with FVC in or near EFEMP1, BMP6, MIR129-2–HSD17B12, PRDM11, WWOX and KCNJ2. Two loci previously associated with spirometric measures (GSTCD and PTCH1) were related to FVC. Newly implicated regions were followed up in samples from African-American, Korean, Chinese and Hispanic individuals. We detected transcripts for all six newly implicated genes in human lung tissue. The new loci may inform mechanisms involved in lung development and the pathogenesis of restrictive lung disease.]]> Sat 24 Mar 2018 07:53:01 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44823 Mon 24 Oct 2022 09:45:54 AEDT ]]>